Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXH0MY
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| Drug Name |
{(S)-1-[2,5-Dioxo-1-(3-phenyl-propyl)-piperidin-4-ylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester
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| Synonyms |
CHEMBL316864
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C31H33N3O5
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| Canonical SMILES |
O=C(N[C@@H](Cc1ccccc1)C(=O)NC2CC(=O)N(CCCc3ccccc3)CC2=O)OCc4ccccc4
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| InChI |
InChI=1S/C31H33N3O5/c35-28-21-34(18-10-17-23-11-4-1-5-12-23)29(36)20-26(28)32-30(37)27(19-24-13-6-2-7-14-24)33-31(38)39-22-25-15-8-3-9-16-25/h1-9,11-16,26-27H,10,17-22H2,(H,32,37)(H,33,38)/t26?,27-/m0/s1
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| InChIKey |
KFSSAMTWPDRZDV-GEVKEYJPSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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