Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXI1ZL
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| Drug Name |
[(S)-1-(1-Isobutyl-2,5-dioxo-piperidin-4-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester
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| Synonyms |
CHEMBL105708
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H31N3O5
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| Canonical SMILES |
CC(C)CN1CC(=O)C(CC1=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc3ccccc3
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| InChI |
InChI=1S/C26H31N3O5/c1-18(2)15-29-16-23(30)21(14-24(29)31)27-25(32)22(13-19-9-5-3-6-10-19)28-26(33)34-17-20-11-7-4-8-12-20/h3-12,18,21-22H,13-17H2,1-2H3,(H,27,32)(H,28,33)/t21?,22-/m0/s1
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| InChIKey |
PXXQXBNYVWENDC-KEKNWZKVSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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