Drug General Information
Drug ID
DXI9HI
Drug Name
4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-1H-quinolin-2-one
Synonyms
CHEMBL344703
Indication Discovery agent Investigative [1587926]
Formula
C26H19Cl2N3O2
Canonical SMILES
Cn1cncc1C(O)(c2ccc(Cl)cc2)c3ccc4nc(O)cc(c5cccc(Cl)c5)c4c3
InChI
InChI=1S/C26H19Cl2N3O2/c1-31-15-29-14-24(31)26(33,17-5-8-19(27)9-6-17)18-7-10-23-22(12-18)21(13-25(32)30-23)16-3-2-4-20(28)11-16/h2-15,33H,1H3,(H,30,32)
InChIKey
YLWZTUJNSOKAOC-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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