Drug General Information
Drug ID
DXJ0QM
Drug Name
(R)-8-chloro-11-(1-methanesulfonyl-piperidin-4-yl)-5-piperazin-1-yl-11H-benzo[5,6]cyclohepta[1,2-b]pyridine
Synonyms
CHEMBL382828
Indication Discovery agent Investigative [1587926]
Formula
C24H29ClN4O2S
Canonical SMILES
CS(=O)(=O)N1CCC(CC1)[C@@H]2c3ccc(Cl)cc3C=C(N4CCNCC4)c5cccnc25
InChI
InChI=1S/C24H29ClN4O2S/c1-32(30,31)29-11-6-17(7-12-29)23-20-5-4-19(25)15-18(20)16-22(28-13-9-26-10-14-28)21-3-2-8-27-24(21)23/h2-5,8,15-17,23,26H,6-7,9-14H2,1H3/t23-/m1/s1
InChIKey
ZIGSEKZLCYCKCR-HSZRJFAPSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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