Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXJ7EX
|
||||
| Drug Name |
N-((S)-3-cyclopentenyl-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopropan-2-yl)furan-2-carboxamide
|
||||
| Synonyms |
CHEMBL1807645
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H30N4O6S
|
||||
| Canonical SMILES |
C[C@@H]1CC[C@H](NC(=O)[C@H](CC2=CCCC2)NC(=O)c3occc3)C(=O)CN1S(=O)(=O)c4ccccn4
|
||||
| InChI |
InChI=1S/C25H30N4O6S/c1-17-11-12-19(21(30)16-29(17)36(33,34)23-10-4-5-13-26-23)27-24(31)20(15-18-7-2-3-8-18)28-25(32)22-9-6-14-35-22/h4-7,9-10,13-14,17,19-20H,2-3,8,11-12,15-16H2,1H3,(H,27,31)(H,28,32)/t17-,19+,20+/m1/s1
|
||||
| InChIKey |
VJBNYTFCTIYDMG-HOJAQTOUSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.