Drug General Information
Drug ID
DXJE5L
Drug Name
Boc-Trp-Phg-Asp-1Nal-NH2
Synonyms
CHEMBL353862
Indication Discovery agent Investigative [1587926]
Formula
C41H44N6O8
Canonical SMILES
CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc3cccc4ccccc34)C(=O)N)c5ccccc5
InChI
InChI=1S/C41H44N6O8/c1-41(2,3)55-40(54)46-32(21-27-23-43-30-19-10-9-18-29(27)30)38(52)47-35(25-13-5-4-6-14-25)39(53)45-33(22-34(48)49)37(51)44-31(36(42)50)20-26-16-11-15-24-12-7-8-17-28(24)26/h4-19,23,31-33,35,43H,20-22H2,1-3H3,(H2,42,50)(H,44,51)(H,45,53)(H,46,54)(H,47,52)(H,48,49)/t31-,32-,33-,35-/m0/s1
InChIKey
RYNRWNJFDSYFLB-TUCRWICHSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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