Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXJE5S
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| Drug Name |
(S)-2-(3-Isopropyl-ureido)-3-methyl-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide
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| Synonyms |
CHEMBL1790992
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H30N4O3
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| Canonical SMILES |
CC[C@@H](C)[C@H](NC(=O)NC(C)C)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C=O
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| InChI |
InChI=1S/C21H30N4O3/c1-5-14(4)19(25-21(28)23-13(2)3)20(27)24-16(12-26)10-15-11-22-18-9-7-6-8-17(15)18/h6-9,11-14,16,19,22H,5,10H2,1-4H3,(H,24,27)(H2,23,25,28)/t14-,16-,19+/m1/s1
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| InChIKey |
WCOMDIVUMMKSKH-OGWOLHLISA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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