Drug Information

Drug General Information
Drug ID
DXK1S3
Drug Name
2-Amino-4-chloro-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-benzamide
Synonyms
CHEMBL72428
Indication Discovery agent Investigative [1587926]
Formula
C23H19ClN4O2
Canonical SMILES
CN1C(=O)C(NC(=O)c2ccc(Cl)cc2N)N=C(c3ccccc3)c4ccccc14
InChI
InChI=1S/C23H19ClN4O2/c1-28-19-10-6-5-9-17(19)20(14-7-3-2-4-8-14)26-21(23(28)30)27-22(29)16-12-11-15(24)13-18(16)25/h2-13,21H,25H2,1H3,(H,27,29)
InChIKey
DBUXURPFXJQWFU-UHFFFAOYSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.