Drug Information

Drug General Information
Drug ID
DXKW1D
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-(1-oxy-pyridin-3-ylmethyl)-piperidine-1-carboxamidine
Synonyms
CHEMBL348395
Indication Discovery agent Investigative [1587926]
Formula
C27H24BrClN6O
Canonical SMILES
[O-][n+]1cccc(C\\N=C(\\NC#N)/N2CCC(=C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC2)c1
InChI
InChI=1S/C27H24BrClN6O/c28-22-12-21-4-3-20-13-23(29)5-6-24(20)25(26(21)31-15-22)19-7-10-34(11-8-19)27(33-17-30)32-14-18-2-1-9-35(36)16-18/h1-2,5-6,9,12-13,15-16H,3-4,7-8,10-11,14H2,(H,32,33)
InChIKey
OBVKAVIOGZYQPA-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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