Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXKX2M
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| Drug Name |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(4-tert-butylpiperazin-1-yl)thiazol-4-yl)benzamide
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| Synonyms |
CHEMBL200708
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H36N6O2S
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| Canonical SMILES |
CC(C)(C)N1CCN(CC1)c2nc(cs2)c3ccc(cc3)C(=O)NC4(CCCCC4)C(=O)NCC#N
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| InChI |
InChI=1S/C27H36N6O2S/c1-26(2,3)33-17-15-32(16-18-33)25-30-22(19-36-25)20-7-9-21(10-8-20)23(34)31-27(11-5-4-6-12-27)24(35)29-14-13-28/h7-10,19H,4-6,11-12,14-18H2,1-3H3,(H,29,35)(H,31,34)
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| InChIKey |
LJDJFTDNISLGMV-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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