Drug Information

Drug General Information
Drug ID
DXL2IF
Drug Name
11-[2-(2-methoxyphenyl)acetyl]-1-phenyl-(1R,8R,9S,13S)-11-azatetracyclo[6.5.2.02,7.09,13]pentadeca-2,4,6-triene-9-methoxycarboxamide (RPR113401)
Synonyms
RPR-113401; CHEMBL301809
Indication Discovery agent Investigative [1587926]
Formula
C31H32N2O4
Canonical SMILES
CONC(=O)[C@]12CN(C[C@H]1[C@]3(CC[C@@H]2c4ccccc34)c5ccccc5)C(=O)Cc6ccccc6OC
InChI
InChI=1S/C31H32N2O4/c1-36-26-15-9-6-10-21(26)18-28(34)33-19-27-30(22-11-4-3-5-12-22)17-16-25(23-13-7-8-14-24(23)30)31(27,20-33)29(35)32-37-2/h3-15,25,27H,16-20H2,1-2H3,(H,32,35)/t25-,27+,30-,31+/m1/s1
InChIKey
JPYDRCUDZCZXCQ-XSVIJKGOSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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