Drug Information

Drug General Information
Drug ID
DXL2UK
Drug Name
1-[(R)-3-Benzyloxy-2-(3-m-tolyl-ureido)-propionyl]-piperidine-4-carboxylic acid phenylamide
Synonyms
CHEMBL322913
Indication Discovery agent Investigative [1587926]
Formula
C30H34N4O4
Canonical SMILES
Cc1cccc(NC(=O)N[C@H](COCc2ccccc2)C(=O)N3CCC(CC3)C(=O)Nc4ccccc4)c1
InChI
InChI=1S/C30H34N4O4/c1-22-9-8-14-26(19-22)32-30(37)33-27(21-38-20-23-10-4-2-5-11-23)29(36)34-17-15-24(16-18-34)28(35)31-25-12-6-3-7-13-25/h2-14,19,24,27H,15-18,20-21H2,1H3,(H,31,35)(H2,32,33,37)/t27-/m1/s1
InChIKey
HSPFWSJPWOITQE-HHHXNRCGSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.