Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXL8PZ
|
||||
| Drug Name |
(S)-3,3-dimethyl-1-(4-(4-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)butan-2-yl(S)-1-(1H-pyrazol-5-ylamino)-1,2-dioxoheptan-3-ylcarbamate
|
||||
| Synonyms |
CHEMBL191584
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H33F3N6O4
|
||||
| Canonical SMILES |
CCCC[C@H](NC(=O)O[C@H](Cn1cnc(c1)c2ccc(cc2)C(F)(F)F)C(C)(C)C)C(=O)C(=O)Nc3ccn[nH]3
|
||||
| InChI |
InChI=1S/C27H33F3N6O4/c1-5-6-7-19(23(37)24(38)34-22-12-13-32-35-22)33-25(39)40-21(26(2,3)4)15-36-14-20(31-16-36)17-8-10-18(11-9-17)27(28,29)30/h8-14,16,19,21H,5-7,15H2,1-4H3,(H,33,39)(H2,32,34,35,38)/t19-,21+/m0/s1
|
||||
| InChIKey |
IBVYZTXPOAZNHM-PZJWPPBQSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.