Drug General Information
Drug ID
DXNZ0I
Drug Name
4-(3-Chlorophenyl)-6-((4-chlorophenyl)(hydroxy)(1-ethyl-1H-imidazol-5-yl)methyl)-1-methylquinolin-2(1H)-one
Synonyms
CHEMBL1094234
Indication Discovery agent Investigative [1587926]
Formula
C28H23Cl2N3O2
Canonical SMILES
CCn1cncc1C(O)(c2ccc(Cl)cc2)c3ccc4N(C)C(=O)C=C(c5cccc(Cl)c5)c4c3
InChI
InChI=1S/C28H23Cl2N3O2/c1-3-33-17-31-16-26(33)28(35,19-7-10-21(29)11-8-19)20-9-12-25-24(14-20)23(15-27(34)32(25)2)18-5-4-6-22(30)13-18/h4-17,35H,3H2,1-2H3
InChIKey
YLGPNUOSRABSDL-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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