Drug Information

Drug General Information
Drug ID
DXO2WT
Drug Name
Lithium; (S)-4-methylsulfanyl-2-({2'-methyl-5-[5-(4-trifluoromethyl-phenyl)-furan-2-ylmethoxymethyl]-biphenyl-2-carbonyl}-amino)-butyrate
Synonyms
CHEMBL428001
Indication Discovery agent Investigative [1587926]
Formula
C32H29F3NO5S.Li
Canonical SMILES
[Li+].CSCC[C@H](NC(=O)c1ccc(COCc2oc(cc2)c3ccc(cc3)C(F)(F)F)cc1c4ccccc4C)C(=O)[O-]
InChI
InChI=1S/C32H30F3NO5S.Li/c1-20-5-3-4-6-25(20)27-17-21(7-13-26(27)30(37)36-28(31(38)39)15-16-42-2)18-40-19-24-12-14-29(41-24)22-8-10-23(11-9-22)32(33,34)35;/h3-14,17,28H,15-16,18-19H2,1-2H3,(H,36,37)(H,38,39);/q;+1/p-1/t28-;/m0./s1
InChIKey
GTXCLHIBVVEXGH-JCOPYZAKSA-M
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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