Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXO6KC
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| Drug Name |
D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-Pro(4-0-n-Propyl)-pro(2,3-dihexyl)-arg
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| Synonyms |
CHEMBL2370157
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C56H91N19O14S
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| Canonical SMILES |
CCCO[C@@H]1C[C@H](N(C1)C(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](N)CCCN=C(N)N)c4cccs4)C(=O)N5C6CCCCC6C[C@H]5C(=O)N[C@@H](CCCN=C(N)N)C(=O)O
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| InChI |
InChI=1S/C56H91N19O14S/c1-2-21-89-32-25-41(52(86)75-37-14-4-3-10-30(37)23-40(75)47(81)69-35(53(87)88)13-7-19-66-56(62)63)74(28-32)50(84)36(29-76)70-48(82)44(42-16-9-22-90-42)71-43(78)26-67-46(80)39-24-31(77)27-73(39)51(85)38-15-8-20-72(38)49(83)34(12-6-18-65-55(60)61)68-45(79)33(57)11-5-17-64-54(58)59/h9,16,22,30-41,44,76-77H,2-8,10-15,17-21,23-29,57H2,1H3,(H,67,80)(H,68,79)(H,69,81)(H,70,82)(H,71,78)(H,87,88)(H4,58,59,64)(H4,60,61,65)(H4,62,63,66)/t30?,31-,32+,33+,34-,35-,36-,37?,38-,39-,40-,41-,44-/m0/s1
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| InChIKey |
SKEDKPUBPAWRPO-YJVSRAMVSA-N
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| Target and Pathway | |||||
| Target(s) | B1 bradykinin receptor | Target Info | [1587926] | ||
| B2 bradykinin receptor | Target Info | [1587926] | |||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Complement and coagulation cascades | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| Regulation of actin cytoskeleton | |||||
| Pathways in cancerhsa04020:Calcium signaling pathway | |||||
| cGMP-PKG signaling pathway | |||||
| Sphingolipid signaling pathway | |||||
| Endocrine and other factor-regulated calcium reabsorption | |||||
| Chagas disease (American trypanosomiasis) | |||||
| Pathways in cancer | |||||
| Pathway Interaction Database | Direct p53 effectors | ||||
| Validated transcriptional targets of deltaNp63 isoforms | |||||
| WikiPathways | Complement and Coagulation Cascades | ||||
| ACE Inhibitor Pathway | |||||
| Regulation of Actin Cytoskeleton | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Vitamin D Receptor Pathway | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP554:ACE Inhibitor Pathway | |||||
| Nifedipine Activity | |||||
| GPCR downstream signaling | |||||
| References | |||||
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