Drug Information

Drug General Information
Drug ID
DXO8KM
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-dimethylamino-butyl)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL415739
Indication Discovery agent Investigative [1587926]
Formula
C27H32BrClN6
Canonical SMILES
CN(C)CCCC\\N=C(\\NC#N)/N1CCC(=C2c3ccc(Cl)cc3CCc4cc(Br)cnc24)CC1
InChI
InChI=1S/C27H32BrClN6/c1-34(2)12-4-3-11-31-27(33-18-30)35-13-9-19(10-14-35)25-24-8-7-23(29)16-20(24)5-6-21-15-22(28)17-32-26(21)25/h7-8,15-17H,3-6,9-14H2,1-2H3,(H,31,33)
InChIKey
ZXOBHVNRVRTWEO-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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