Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXP2OD
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| Drug Name |
N-((S)-3-(naphthalen-2-yl)-1-oxo-1-((S)-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)propan-2-yl)-1-naphthamide
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| Synonyms |
CHEMBL194643
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C35H32N4O5S
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| Canonical SMILES |
O=C(N[C@H]1CCCN(CC1=O)S(=O)(=O)c2ccccn2)[C@H](Cc3ccc4ccccc4c3)NC(=O)c5cccc6ccccc56
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| InChI |
InChI=1S/C35H32N4O5S/c40-32-23-39(45(43,44)33-16-5-6-19-36-33)20-8-15-30(32)37-35(42)31(22-24-17-18-25-9-1-2-11-27(25)21-24)38-34(41)29-14-7-12-26-10-3-4-13-28(26)29/h1-7,9-14,16-19,21,30-31H,8,15,20,22-23H2,(H,37,42)(H,38,41)/t30-,31-/m0/s1
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| InChIKey |
BLJKFTVYZPTNBP-CONSDPRKSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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