Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXP4LO
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| Drug Name |
2-((E)-2-Benzenesulfonyl-vinylamino)-N-[3-methyl-1-(3-morpholin-4-yl-ureidocarbonyl)-butyl]-4-phenyl-butyramide
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| Synonyms |
CHEMBL3142832
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H39N5O6S
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N\\C=C\\S(=O)(=O)c2ccccc2)C(=O)NC(=O)NN3CCOCC3
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| InChI |
InChI=1S/C29H39N5O6S/c1-22(2)21-26(28(36)32-29(37)33-34-16-18-40-19-17-34)31-27(35)25(14-13-23-9-5-3-6-10-23)30-15-20-41(38,39)24-11-7-4-8-12-24/h3-12,15,20,22,25-26,30H,13-14,16-19,21H2,1-2H3,(H,31,35)(H2,32,33,36,37)/b20-15+/t25-,26-/m0/s1
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| InChIKey |
GMUXXTCOBZDVFS-DJCCSWQUSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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