Drug General Information
Drug ID
DXPF3F
Drug Name
3-(4-(4-chlorophenyl)piperazin-1-yl)-1-phenylpropan-1-one
Synonyms
CHEMBL424470
Indication Discovery agent Investigative [1587926]
Formula
C19H21ClN2O
Canonical SMILES
Clc1ccc(cc1)N2CCN(CCC(=O)c3ccccc3)CC2
InChI
InChI=1S/C19H21ClN2O/c20-17-6-8-18(9-7-17)22-14-12-21(13-15-22)11-10-19(23)16-4-2-1-3-5-16/h1-9H,10-15H2
InChIKey
WSPGJGOBUJGMBV-UHFFFAOYSA-N
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapsehsa04726:Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathwayP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signalingWP727:Monoamine Transport
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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