Drug General Information
Drug ID
DXR7ZW
Drug Name
N-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]sulfamide
Synonyms
CHEMBL2337527
Indication Discovery agent Investigative [1587926]
Formula
C6H14N2O6S
Canonical SMILES
C[C@@H]1O[C@@H](NS(=O)(=O)N)[C@@H](O)[C@H](O)[C@H]1O
InChI
InChI=1S/C6H14N2O6S/c1-2-3(9)4(10)5(11)6(14-2)8-15(7,12)13/h2-6,8-11H,1H3,(H2,7,12,13)/t2-,3-,4+,5-,6+/m0/s1
InChIKey
JRZLSPHVEFMWQW-MDMQIMBFSA-N
Target and Pathway
Target(s) Carbonic anhydrase IX Target Info [1587926]
Carbonic anhydrase XII Target Info [1587926]
KEGG Pathway Nitrogen metabolismhsa00910:Nitrogen metabolism
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database HIF-1-alpha transcription factor network
Reactome Regulation of gene expression by Hypoxia-inducible Factor
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxide
WikiPathways Vitamin D Receptor Pathway
Reversible Hydration of Carbon Dioxide
Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon Dioxide
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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