Drug Information

Drug General Information
Drug ID
DXS7KN
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclohexylamide 2-{[2-(1H-imidazol-4-yl)-ethyl]-amide}
Synonyms
CHEMBL201844
Indication Discovery agent Investigative [1587926]
Formula
C31H37BrClN7O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCCc4c[nH]cn4)C(=O)NC5CCCCC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C31H37BrClN7O2/c32-22-14-21-7-6-20-15-23(33)8-9-26(20)29(28(21)36-16-22)39-12-13-40(31(42)38-24-4-2-1-3-5-24)27(18-39)30(41)35-11-10-25-17-34-19-37-25/h8-9,14-17,19,24,27,29H,1-7,10-13,18H2,(H,34,37)(H,35,41)(H,38,42)
InChIKey
HQHGMTIPVQADEA-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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