Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXU6H2
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| Drug Name |
4-Benzenesulfonylamino-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-3-methyl-benzamide
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| Synonyms |
CHEMBL473654
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H37N3O6S
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| Canonical SMILES |
CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC2(C)CCCC2)NC(=O)c3ccc(NS(=O)(=O)c4ccccc4)c(C)c3
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| InChI |
InChI=1S/C29H37N3O6S/c1-4-25-26(24(33)18-38-25)31-28(35)23(17-29(3)14-8-9-15-29)30-27(34)20-12-13-22(19(2)16-20)32-39(36,37)21-10-6-5-7-11-21/h5-7,10-13,16,23,25-26,32H,4,8-9,14-15,17-18H2,1-3H3,(H,30,34)(H,31,35)/t23-,25-,26+/m0/s1
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| InChIKey |
ZTAFLDIJAATCDC-AYRHNUGRSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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