Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXU8EO
|
||||
| Drug Name |
Naphthalene-1-carboxylic acid{3-methyl-1-[(S)-(S)-3-oxo-1-(pyridine-2-sulfonyl)-azepan-4-ylcarbamoyl]-butyl}-amide
|
||||
| Synonyms |
CHEMBL382286
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H32N4O5S
|
||||
| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1cccc2ccccc12)C(=O)N[C@H]3CCCN(CC3=O)S(=O)(=O)c4ccccn4
|
||||
| InChI |
InChI=1S/C28H32N4O5S/c1-19(2)17-24(31-27(34)22-12-7-10-20-9-3-4-11-21(20)22)28(35)30-23-13-8-16-32(18-25(23)33)38(36,37)26-14-5-6-15-29-26/h3-7,9-12,14-15,19,23-24H,8,13,16-18H2,1-2H3,(H,30,35)(H,31,34)/t23-,24-/m0/s1
|
||||
| InChIKey |
AWEFNCACPBKWGG-ZEQRLZLVSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.