Drug General Information
Drug ID
DXUM5F
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclohexylamide 2-[(3,5-dimethyl-isoxazol-4-ylmethyl)-amide]
Synonyms
CHEMBL382506
Indication Discovery agent Investigative [1587926]
Formula
C32H38BrClN6O3
Canonical SMILES
Cc1onc(C)c1CNC(=O)C2CN(CCN2C(=O)NC3CCCCC3)C4c5ccc(Cl)cc5CCc6cc(Br)cnc46
InChI
InChI=1S/C32H38BrClN6O3/c1-19-27(20(2)43-38-19)17-36-31(41)28-18-39(12-13-40(28)32(42)37-25-6-4-3-5-7-25)30-26-11-10-24(34)15-21(26)8-9-22-14-23(33)16-35-29(22)30/h10-11,14-16,25,28,30H,3-9,12-13,17-18H2,1-2H3,(H,36,41)(H,37,42)
InChIKey
XJLKHBJYSDKRSX-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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