Drug Information
Drug General Information | |||||
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Drug ID |
DXV2FF
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Drug Name |
CHEMBL410193
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Synonyms |
2-hydroxy-N-{[(3-hydroxy-2-methyl-6-{[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl]oxy}oxan-4-yl)amino]methyl}-5-[(14E)-1-{4-[(1E)-1-(4-hydroxyphenyl)-2-phenylbut-1-en-1-yl]phenyl}-4-methyl-1,7,10,13-tetraoxa-4,14-diazapentadec-14-en-15-yl]benzamide
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C67H74N4O18
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Canonical SMILES |
CC\\C(=C(\\c1ccc(O)cc1)/c2ccc(OCCN(C)CCOCCOCCO\\N=C\\c3ccc(O)c(c3)C(=O)NCNC4CC(O[C@H]5C[C@@](O)(Cc6c(O)c7C(=O)c8cccc(OC)c8C(=O)c7c(O)c56)C(=O)CO)OC(C)C4O)cc2)\\c9ccccc9
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InChI |
InChI=1S/C67H74N4O18/c1-5-46(41-10-7-6-8-11-41)56(42-15-19-44(73)20-16-42)43-17-21-45(22-18-43)86-27-25-71(3)24-26-84-28-29-85-30-31-87-70-36-40-14-23-51(74)48(32-40)66(81)69-38-68-50-33-55(88-39(2)61(50)76)89-53-35-67(82,54(75)37-72)34-49-58(53)65(80)60-59(63(49)78)62(77)47-12-9-13-52(83-4)57(47)64(60)79/h6-23,32,36,39,50,53,55,61,68,72-74,76,78,80,82H,5,24-31,33-35,37-38H2,1-4H3,(H,69,81)/b56-46+,70-36+/t39?,50?,53-,55?,61?,67-/m0/s1
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InChIKey |
ZONUJWGGPOQYBT-DIDVDAKUSA-N
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Target and Pathway | |||||
Target(s) | Estrogen receptor beta | Target Info | [1587926] | ||
Estrogen receptor | Target Info | [1587926] | |||
Pathway Interaction Database | Plasma membrane estrogen receptor signaling | ||||
Validated nuclear estrogen receptor beta network | |||||
Validated nuclear estrogen receptor alpha networksmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling | |||||
Signaling events mediated by HDAC Class II | |||||
LKB1 signaling events | |||||
Regulation of Telomerase | |||||
ATF-2 transcription factor network | |||||
AP-1 transcription factor network | |||||
FOXM1 transcription factor network | |||||
Validated nuclear estrogen receptor alpha network | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
FOXA1 transcription factor network | |||||
WikiPathways | SIDS Susceptibility Pathways | ||||
Ovarian Infertility Genes | |||||
Integrated Pancreatic Cancer Pathway | |||||
Nuclear ReceptorsWP712:Estrogen signaling pathway | |||||
Nuclear Receptors Meta-Pathway | |||||
Estrogen Receptor Pathway | |||||
Signaling by ERBB4 | |||||
JAK/STAT | |||||
Leptin signaling pathway | |||||
miR-targeted genes in muscle cell - TarBase | |||||
Integrated Breast Cancer Pathway | |||||
Nuclear Receptors | |||||
References |
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