Drug General Information
Drug ID
DXVQ0J
Drug Name
4-[(3-Chlorophenyl)methyl]-2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-1(2H)-phthalazinone
Synonyms
CHEMBL1767146
Indication Discovery agent Investigative [1587926]
Formula
C21H22ClN3O
Canonical SMILES
CN1CCC[C@@H]1CN2N=C(Cc3cccc(Cl)c3)c4ccccc4C2=O
InChI
InChI=1S/C21H22ClN3O/c1-24-11-5-8-17(24)14-25-21(26)19-10-3-2-9-18(19)20(23-25)13-15-6-4-7-16(22)12-15/h2-4,6-7,9-10,12,17H,5,8,11,13-14H2,1H3/t17-/m1/s1
InChIKey
YEFYNZHDZSJWCN-QGZVFWFLSA-N
Target and Pathway
Target(s) Alpha-1 adrenergic receptor Target Info [1587926]
Histamine H1 receptor Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.