Drug Information
Drug General Information | |||||
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Drug ID |
DXW0R3
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Drug Name |
N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-3-methanesulfonylamino-benzamide
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Synonyms |
CHEMBL481503
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C23H33N3O6S
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Canonical SMILES |
CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC2(C)CCCC2)NC(=O)c3cccc(NS(=O)(=O)C)c3
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InChI |
InChI=1S/C23H33N3O6S/c1-4-19-20(18(27)14-32-19)25-22(29)17(13-23(2)10-5-6-11-23)24-21(28)15-8-7-9-16(12-15)26-33(3,30)31/h7-9,12,17,19-20,26H,4-6,10-11,13-14H2,1-3H3,(H,24,28)(H,25,29)/t17-,19-,20+/m0/s1
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InChIKey |
LTPMAMKKBKZMKQ-YSIASYRMSA-N
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Target and Pathway | |||||
Target(s) | Cathepsin K | Target Info | [1587926] | ||
Cathepsin L | Target Info | [1587926] | |||
Reactome | Collagen degradation | ||||
Degradation of the extracellular matrix | |||||
Activation of Matrix Metalloproteinases | |||||
Trafficking and processing of endosomal TLR | |||||
MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
Assembly of collagen fibrils and other multimeric structures | |||||
MHC class II antigen presentation | |||||
References |
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