Drug Information
| Drug General Information | |||||
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| Drug ID |
DXX6I5
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| Drug Name |
3-Acetyl-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-methanesulfonylamino-benzamide
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| Synonyms |
CHEMBL481227
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H35N3O7S
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| Canonical SMILES |
CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC2(C)CCCC2)NC(=O)c3ccc(NS(=O)(=O)C)c(c3)C(=O)C
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| InChI |
InChI=1S/C25H35N3O7S/c1-5-21-22(20(30)14-35-21)27-24(32)19(13-25(3)10-6-7-11-25)26-23(31)16-8-9-18(28-36(4,33)34)17(12-16)15(2)29/h8-9,12,19,21-22,28H,5-7,10-11,13-14H2,1-4H3,(H,26,31)(H,27,32)/t19-,21-,22+/m0/s1
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| InChIKey |
JHYLMMFATBCMQI-ILWGZMRPSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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