Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXXL3Q
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| Drug Name |
2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid [2-(4-methoxyphenyl)-ethyl]-amide
|
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| Synonyms |
CHEMBL218024
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H25N5O2
|
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| Canonical SMILES |
COc1ccc(CCNC(=O)c2cnc(nc2NC3CCCCC3)C#N)cc1
|
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| InChI |
InChI=1S/C21H25N5O2/c1-28-17-9-7-15(8-10-17)11-12-23-21(27)18-14-24-19(13-22)26-20(18)25-16-5-3-2-4-6-16/h7-10,14,16H,2-6,11-12H2,1H3,(H,23,27)(H,24,25,26)
|
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| InChIKey |
VLROHFCAQABUTJ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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