Drug Information

Drug General Information
Drug ID
DXY3HG
Drug Name
2-(1-Acetyl-piperidin-3-yl)-1-[4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-ethanone
Synonyms
CHEMBL171073
Indication Discovery agent Investigative [1587926]
Formula
C27H33ClN4O2
Canonical SMILES
CC(=O)N1CCCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)C1
InChI
InChI=1S/C27H33ClN4O2/c1-19(33)32-11-3-4-20(18-32)16-25(34)30-12-14-31(15-13-30)27-24-9-8-23(28)17-22(24)7-6-21-5-2-10-29-26(21)27/h2,5,8-10,17,20,27H,3-4,6-7,11-16,18H2,1H3
InChIKey
NACLMRMBLJHXKV-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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