Drug Information

Drug General Information
Drug ID
DXZ0VE
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(phenyl)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL346039
Indication Discovery agent Investigative [1587926]
Formula
C27H23BrClN5
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/c4ccccc4)\\NC#N)c5ncc(Br)cc5CCc2c1
InChI
InChI=1S/C27H23BrClN5/c28-21-14-20-7-6-19-15-22(29)8-9-24(19)25(26(20)31-16-21)18-10-12-34(13-11-18)27(32-17-30)33-23-4-2-1-3-5-23/h1-5,8-9,14-16H,6-7,10-13H2,(H,32,33)
InChIKey
NWDQSMCMVBTTJD-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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