Drug General Information
Drug ID
DXZ5KF
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-pyridin-4-yl-piperidine-1-carboxamidine
Synonyms
CHEMBL358448
Indication Discovery agent Investigative [1587926]
Formula
C26H22BrClN6
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/c4ccncc4)\\NC#N)c5ncc(Br)cc5CCc2c1
InChI
InChI=1S/C26H22BrClN6/c27-20-13-19-2-1-18-14-21(28)3-4-23(18)24(25(19)31-15-20)17-7-11-34(12-8-17)26(32-16-29)33-22-5-9-30-10-6-22/h3-6,9-10,13-15H,1-2,7-8,11-12H2,(H,30,32,33)
InChIKey
RLOIBKDTMWTLDZ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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