Drug Information

Drug General Information
Drug ID
D00CDF
Former ID
DIB018851
Drug Name
andarine
Synonyms
GTX007; GTX-007
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530128]
Structure
Download
2D MOL
Formula
C19H18F3N3O6
InChI
InChI=1S/C19H18F3N3O6/c1-11(26)23-12-3-6-14(7-4-12)31-10-18(2,28)17(27)24-13-5-8-16(25(29)30)15(9-13)19(20,21)22/h3-9,28H,10H2,1-2H3,(H,23,26)(H,24,27)/t18-/m0/s1
InChIKey
YVXVTLGIDOACBJ-SFHVURJKSA-N
PubChem Compound ID
9824562
PubChem Substance ID
14783679, 16356819, 24127334, 44922700, 46518728, 50075683, 51091126, 77753267, 87325162, 87557517, 99436998, 99443894, 103354676, 109692985, 118843816, 121380285, 124757027, 125163831, 126671644, 131480700, 136340309, 136367327, 136368098, 137006451, 137275994, 142268276, 144115609, 151980501, 152258346, 152344170, 160647184, 160657742, 160968502, 162011824, 162037461, 164042433, 164827207, 170497626, 172650052, 172914177, 174529284, 177749786, 184819094, 188899523, 198981980, 223366179, 223556770, 223669590, 223704968, 228777798
Target and Pathway
Target(s) mRNA of androgen receptor Target Info Agonist [530128]
KEGG Pathway Oocyte meiosis
Pathways in cancer
Prostate cancer
NetPath Pathway EGFR1 Signaling Pathway
AndrogenReceptor Signaling Pathway
FSH Signaling Pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
Coregulation of Androgen receptor activity
Regulation of Androgen receptor activity
Nongenotropic Androgen signaling
Regulation of nuclear beta catenin signaling and target gene transcription
FOXA1 transcription factor network
Notch-mediated HES/HEY network
Reactome Nuclear Receptor transcription pathway
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
WikiPathways SIDS Susceptibility Pathways
Integrated Pancreatic Cancer Pathway
Prostate Cancer
Integrated Breast Cancer Pathway
Nuclear Receptors
Androgen receptor signaling pathway
References
Ref 530128Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit. J Med Chem. 2009 Jun 25;52(12):3597-617.
Ref 530128Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit. J Med Chem. 2009 Jun 25;52(12):3597-617.

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