Drug Information

Drug General Information
Drug ID
D00CLB
Former ID
DNC009267
Drug Name
SB-328872
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529558]
Structure
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2D MOL

3D MOL
Formula
C31H42N4O3S
Canonical SMILES
CC(C)CC(C(=O)NC1CCN(C1)CC2=CC=C(C=C2)OCCCN(C)C)NC(=O)C3<br />=CC4=CC=CC=C4S3
InChI
1S/C31H42N4O3S/c1-22(2)18-27(33-31(37)29-19-24-8-5-6-9-28(24)39-29)30(36)32-25-14-16-35(21-25)20-23-10-12-26(13-11-23)38-17-7-15-34(3)4/h5-6,8-13,19,22,25,27H,7,14-18,20-21H2,1-4H3,(H,32,36)(H,33,37)/t25-,27-/m0/s1
InChIKey
HLMWNBIZKQIDFC-BDYUSTAISA-N
PubChem Compound ID
10120078
Target and Pathway
Target(s) Urotensin II receptor Target Info Inhibitor [529558]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 529558Bioorg Med Chem Lett. 2008 Jul 15;18(14):3950-4. Epub 2008 Jun 10.Urotensin-II receptor antagonists: synthesis and SAR of N-cyclic azaalkyl benzamides.
Ref 529558Bioorg Med Chem Lett. 2008 Jul 15;18(14):3950-4. Epub 2008 Jun 10.Urotensin-II receptor antagonists: synthesis and SAR of N-cyclic azaalkyl benzamides.

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