Drug Information

Drug General Information
Drug ID
D00CLC
Former ID
DIB009451
Drug Name
SLV-338
Indication Cardiovascular disorder [ICD10:I00-I99] Phase 1 [531611]
Company
Solvay SA
Target and Pathway
Target(s) Neutral endopeptidase Target Info Modulator [531611]
Endothelin converting enzyme Target Info Modulator [531611]
KEGG Pathway Renin-angiotensin system
Hematopoietic cell lineage
Protein digestion and absorption
Alzheimer's disease
NetPath Pathway EGFR1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways Metabolism of Angiotensinogen to Angiotensins
Primary Focal Segmental Glomerulosclerosis FSGS
Alzheimers Disease
References
Ref 531611Renoprotective effects of combined endothelin-converting enzyme/neutral endopeptidase inhibitor SLV338 in acute and chronic experimental renal damage. Clin Lab. 2011;57(7-8):507-15.
Ref 531611Renoprotective effects of combined endothelin-converting enzyme/neutral endopeptidase inhibitor SLV338 in acute and chronic experimental renal damage. Clin Lab. 2011;57(7-8):507-15.

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