Drug Information

Drug General Information
Drug ID
D00EJS
Former ID
DIB018650
Drug Name
5-hydroxyindole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539446]
Structure
Download
2D MOL
Formula
C8H7NO
InChI
InChI=1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
InChIKey
LMIQERWZRIFWNZ-UHFFFAOYSA-N
PubChem Compound ID
16054
PubChem Substance ID
124179, 865950, 1095774, 3133454, 6350007, 8162040, 10512306, 11448789, 15219012, 24724302, 24895561, 25623560, 26683833, 29198238, 29283945, 37361598, 38233547, 39213069, 49747720, 49747721, 49831582, 49984675, 57329232, 79265822, 84981911, 85086789, 87361533, 87570680, 87692414, 92710588, 93620007, 99214837, 99343703, 103578866, 104338805, 117615493, 117653084, 117775957, 124441732, 124784875, 125342142, 126539872, 126575934, 126588512, 126593797, 126607614, 126614900, 126631724, 126637137, 126658095
Target and Pathway
Target(s) 5-hydroxytryptamine receptor 3A Target Info Modulator (allosteric modulator) [529253]
KEGG Pathway Serotonergic synapse
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway 5HT3 type receptor mediated signaling pathway
Reactome Ligand-gated ion channel transport
WikiPathways SIDS Susceptibility Pathways
Iron uptake and transport
References
Ref 539446(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2295).
Ref 529253The 5-HT3B subunit confers spontaneous channel opening and altered ligand properties of the 5-HT3 receptor. J Biol Chem. 2008 Mar 14;283(11):6826-31.

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