Drug General Information
Drug ID	D00FHI
Former ID	DIB002014
Drug Name	Zabiciprilat
Synonyms	Zabicipril; S-10211; S-9650
Drug Type	Small molecular drug
Indication	Hypertension [ICD9: 401; ICD10:I10-I16]		Discontinued in Phase 2	[544560]
Company	Servier
Structure		Download 2D MOL 3D MOL
Formula	C21H28N2O5
Canonical SMILES	N1(C(=O)[C@@H](N[C@H](C(=O)O)CCc2ccccc2)C)[C@H](C(=O)O)<br />C2CCC1CC2
PubChem Compound ID	65680
Target and Pathway
Target(s)	Angiotensin-converting enzyme	Target Info	Inhibitor	[533956]
KEGG Pathway	Renin-angiotensin system
	Chagas disease (American trypanosomiasis)
	Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway	Angiotensin Metabolism
Reactome	Metabolism of Angiotensinogen to Angiotensins
WikiPathways	ACE Inhibitor Pathway
	Metabolism of Angiotensinogen to Angiotensins
References
Ref 544560	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000139)
Ref 533956	Enzyme immunoassays for a new angiotensin-converting enzyme inhibitor, zabicipril, and its active metabolite in human plasma: application to pharmacokinetic studies. Ther Drug Monit. 1993 Oct;15(5):448-54.

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