Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00HIB
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| Former ID |
DNC000378
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| Drug Name |
Caffeic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [468218] | ||
| Structure |
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Download2D MOL |
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| Formula |
C9H8O4
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| InChI |
InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+
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| InChIKey |
QAIPRVGONGVQAS-DUXPYHPUSA-N
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| CAS Number |
CAS 331-39-5
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| PubChem Compound ID | |||||
| PubChem Substance ID |
4422, 4652, 106262, 491233, 598027, 611234, 855772, 3132907, 8001577, 8034051, 8145667, 9287032, 10518882, 11537800, 14718166, 15171314, 17404771, 22394958, 22395875, 24278290, 24881776, 24881777, 26612575, 26679411, 26746990, 26751505, 26758358, 29203902, 33749646, 46504491, 48413363, 48422454, 49699041, 49703794, 49747047, 49855355, 50104061, 50104062, 50104063, 50104064, 50104065, 53777314, 53787916, 56422203, 57408588, 57651712, 58034488, 74966461, 81040420, 81091163
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| ChEBI ID |
ChEBI:17395
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| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Inhibitor | [535256], [536714], [536829] | |
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| References | |||||
| Ref 535256 | Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126. J Neurosci Res. 2001 Sep 15;65(6):565-72. | ||||
| Ref 536714 | Protection of mouse brain from aluminum-induced damage by caffeic acid. CNS Neurosci Ther. 2008 Spring;14(1):10-6. | ||||
| Ref 536829 | Phenidone protects the nigral dopaminergic neurons from LPS-induced neurotoxicity. Neurosci Lett. 2008 Nov 7;445(1):1-6. Epub 2008 Aug 22. | ||||
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