Drug General Information
Drug ID	D00IFJ
Former ID	DNC003846
Drug Name	1,2,5,6-tetrahydro pyrido[1,2-a]quinolin-3-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[525881]
Structure		Download 2D MOL 3D MOL
Formula	C13H13NO
Canonical SMILES	C1CC2=CC(=O)CCN2C3=CC=CC=C31
InChI	1S/C13H13NO/c15-12-7-8-14-11(9-12)6-5-10-3-1-2-4-13(10)14/h1-4,9H,5-8H2
InChIKey	OPJKPSOLCGGXEW-UHFFFAOYSA-N
PubChem Compound ID	10081476
Target and Pathway
Target(s)	3-oxo-5-alpha-steroid 4-dehydrogenase 1	Target Info	Inhibitor	[525881]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Allopregnanolone biosynthesis
	Androgen biosynthesis
KEGG Pathway	Steroid hormone biosynthesis
NetPath Pathway	IL2 Signaling Pathway
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	Androgen biosynthesis
References
Ref 525881	J Med Chem. 2000 Oct 5;43(20):3718-35.Benzo[c]quinolizin-3-ones: a novel class of potent and selective nonsteroidal inhibitors of human steroid 5alpha-reductase 1.
Ref 525881	J Med Chem. 2000 Oct 5;43(20):3718-35.Benzo[c]quinolizin-3-ones: a novel class of potent and selective nonsteroidal inhibitors of human steroid 5alpha-reductase 1.

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