Drug Information

Drug General Information
Drug ID
D00JBC
Former ID
DNC003762
Drug Name
1-Butyl-3-methyl-3,7-dihydro-purine-2,6-dione
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526756]
Structure
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2D MOL

3D MOL
Formula
C10H14N4O2
Canonical SMILES
CCCCN1C(=O)C2=C(N=CN2)N(C1=O)C
InChI
1S/C10H14N4O2/c1-3-4-5-14-9(15)7-8(12-6-11-7)13(2)10(14)16/h6H,3-5H2,1-2H3,(H,11,12)
InChIKey
GDRIWEXJHHARCU-UHFFFAOYSA-N
PubChem Compound ID
12905389
Target and Pathway
Target(s) Type IV phosphodiesterase Target Info Inhibitor [526756]
CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [526756]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addictionhsa00230:Purine metabolism
Morphine addiction
PathWhiz Pathway Purine Metabolism
Reactome DARPP-32 events
G alpha (s) signalling eventsR-HSA-180024:DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
Myometrial Relaxation and Contraction Pathways
TSH signaling pathwayWP35:G Protein Signaling Pathways
References
Ref 526756J Med Chem. 1992 Oct 30;35(22):4039-44.Effects of alkyl substitutions of xanthine skeleton on bronchodilation.
Ref 526756J Med Chem. 1992 Oct 30;35(22):4039-44.Effects of alkyl substitutions of xanthine skeleton on bronchodilation.

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