Drug General Information
Drug ID	D00RJB
Former ID	DIB014546
Drug Name	Rilopirox
Synonyms	Riloprox; Hoe-351
Drug Type	Small molecular drug
Indication	Fungal infections [ICD9: 110-118; ICD10:B35-B49]		Phase 2	[546060]
Company	Hoechst AG
Structure		Download 2D MOL 3D MOL
Formula	C19H16ClNO4
Canonical SMILES	n1(c(cc(cc1=O)C)COc1ccc(Oc2ccc(Cl)cc2)cc1)O
CAS Number	CAS 104153-37-9
PubChem Compound ID	71778
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Inhibitor	[529413]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 546060	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006112)
Ref 529413	Therapy of seborrheic eczema with an antifungal agent with an antiphlogistic effect. Mycoses. 1991;34 Suppl 1:91-3.

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