Drug Information

Drug General Information
Drug ID
D00WOT
Former ID
DIB008941
Drug Name
CDP-850
Synonyms
VLA-4, Celltech; Anti-E-selectin antibody, Celltech
Drug Type
Antibody
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Discontinued in Phase 2 [546284]
Company
UCB Celltech
CAS Number
CAS 339152-85-1
Target and Pathway
Target(s) P-selectin Target Info [550936]
KEGG Pathway Cell adhesion molecules (CAMs)
Malaria
Staphylococcus aureus infection
Pathway Interaction Database IL4-mediated signaling events
amb2 Integrin signaling
Reactome Platelet degranulation
Cell surface interactions at the vascular wall
WikiPathways Human Complement System
Spinal Cord Injury
Cell surface interactions at the vascular wall
References
Ref 546284Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007242)
Ref 550936WO patent application no. 2001,0276,21, Competitive inhibition elisa for antibody detection.

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