Drug General Information
Drug ID
D00WSN
Former ID
DNC008057
Drug Name
N-(2-morpholinophenyl)-5-nitrofuran-2-carboxamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529071]
Structure
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2D MOL

3D MOL

Formula
C15H15N3O5
Canonical SMILES
C1COCCN1C2=CC=CC=C2NC(=O)C3=CC=C(O3)[N+](=O)[O-]
InChI
1S/C15H15N3O5/c19-15(13-5-6-14(23-13)18(20)21)16-11-3-1-2-4-12(11)17-7-9-22-10-8-17/h1-6H,7-10H2,(H,16,19)
InChIKey
BIQWNNXDPVEAPZ-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Macrophage colony-stimulating factor receptor Target Info Inhibitor [529071]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Pathways in cancer
NetPath Pathway Leptin Signaling Pathway
RANKL Signaling Pathway
References
Ref 529071Bioorg Med Chem Lett. 2007 Nov 15;17(22):6070-4. Epub 2007 Sep 19.Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents.
Ref 529071Bioorg Med Chem Lett. 2007 Nov 15;17(22):6070-4. Epub 2007 Sep 19.Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents.

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