Drug Information

Drug General Information
Drug ID
D00YVR
Former ID
DIB020599
Drug Name
oleamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539878]
Structure
Download
2D MOL
Formula
C18H35NO
InChI
InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-
InChIKey
FATBGEAMYMYZAF-KTKRTIGZSA-N
PubChem Compound ID
5283387
PubChem Substance ID
87668, 585266, 7887303, 10517713, 11038950, 11113753, 14848775, 26751932, 26751933, 26751934, 39316798, 47959446, 48334200, 48417534, 48420782, 49703514, 49846842, 49998733, 50104610, 53788812, 56365478, 57298450, 57358917, 57391339, 76732824, 87350517, 87574113, 91746390, 92309905, 93374599, 98458014, 99300819, 99302337, 103178862, 104046474, 113859930, 124886950, 126524367, 126688203, 134975607, 135626138, 135651530, 137019767, 142454778, 144207642, 144226852, 162174807, 162227355, 163414984, 163849314
Target and Pathway
Target(s) 5-hydroxytryptamine 7 receptor Target Info Modulator (allosteric modulator) [525635]
KEGG Pathway Ras signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 539878(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 284).
Ref 525635Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine7 receptors. Biochem Pharmacol. 1999 Dec 1;58(11):1807-13.

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