Drug General Information
Drug ID	D01AGR
Former ID	DNC008885
Drug Name	1-[5-(4-Chlorophenyl)-2-furoyl]piperazine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529491]
Structure		Download 2D MOL 3D MOL
Formula	C15H15ClN2O2
PubChem Compound ID	24857857
Target and Pathway
Target(s)	PN3 Na+ channel	Target Info	Inhibitor	[529491]
	Voltage-gated sodium channel subunit alpha Nav1.8	Target Info	Inhibitor	[529491]
	Sodium channel protein type 5 subunit alpha	Target Info	Inhibitor	[529491]
KEGG Pathway	Adrenergic signaling in cardiomyocytes
PathWhiz Pathway	Muscle/Heart Contraction
Reactome	Interaction between L1 and AnkyrinsR-HSA-445095:Interaction between L1 and Ankyrins
WikiPathways	SIDS Susceptibility Pathways
	Cardiac Progenitor Differentiation
References
Ref 529491	Bioorg Med Chem. 2008 Jun 15;16(12):6379-86. Epub 2008 May 6.Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain.
Ref 529491	Bioorg Med Chem. 2008 Jun 15;16(12):6379-86. Epub 2008 May 6.Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain.

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