Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01ASJ
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| Former ID |
DIB008334
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| Drug Name |
Nalbuphine hydrochloride ER
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| Synonyms |
PW-4142; Nalbuphine hydrochloride ER (oral, pain, TIMERx); Nalbuphine (oral, extended release, Geminex), Penwest; Nalbuphine (oral, extended release, TIMERx), Penwest; Nalbuphine ER (oral, pain, Geminex), Penwest; Nalbuphine ER (oral, pain, TIMERx), Penwest; Nalbuphine hydrochloride (oral, extended release, TIMERx), Penwest; Nalbuphine hydrochloride ER (oral, pain, TIMERx), Penwest
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| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Phase 3 | [521828] | ||
| Company |
Penwest Pharmaceuticals Co
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC<br />6CCC6)c45
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| InChI |
1S/C21H27NO4/c23-14-5-4-13-10-16-21(25)7-6-15(24)19-20(21,17(13)18(14)26-19)8-9-22(16)11-12-2-1-3-12/h4-5,12,15-16,19,23-25H,1-3,6-11H2/t15-,16+,19-,20-,21+/m0/s1
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| InChIKey |
NETZHAKZCGBWSS-CEDHKZHLSA-N
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| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Modulator | ||
| Kappa-type opioid receptor | Target Info | Modulator | |||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
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