Drug General Information
Drug ID	D01CYI
Former ID	DNC006397
Drug Name	7-hydroxy-3-(4-hydroxyphenyl)-3H-quinazolin-4-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528131]
Structure		Download 2D MOL 3D MOL
Formula	C14H10N2O3
Canonical SMILES	C1=CC(=CC=C1N2C=NC3=C(C2=O)C=CC(=C3)O)O
InChI	1S/C14H10N2O3/c17-10-3-1-9(2-4-10)16-8-15-13-7-11(18)5-6-12(13)14(16)19/h1-8,17-18H
InChIKey	NECCEJFVHJYYDA-UHFFFAOYSA-N
PubChem Compound ID	11579721
Target and Pathway
Target(s)	Estrogen receptor beta	Target Info	Inhibitor	[528131]
KEGG Pathway	Estrogen signaling pathway
	Prolactin signaling pathway
Pathway Interaction Database	Plasma membrane estrogen receptor signaling
	Validated nuclear estrogen receptor beta network
	Validated nuclear estrogen receptor alpha network
Reactome	Nuclear Receptor transcription pathway
WikiPathways	SIDS Susceptibility Pathways
	Ovarian Infertility Genes
	Integrated Pancreatic Cancer Pathway
	Nuclear Receptors
References
Ref 528131	J Med Chem. 2006 Apr 20;49(8):2440-55.Synthesis and characterization of 3-arylquinazolinone and 3-arylquinazolinethione derivatives as selective estrogen receptor beta modulators.
Ref 528131	J Med Chem. 2006 Apr 20;49(8):2440-55.Synthesis and characterization of 3-arylquinazolinone and 3-arylquinazolinethione derivatives as selective estrogen receptor beta modulators.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.