TTD | Drug: D01KVG

Drug General Information
Drug ID	D01KVG
Former ID	DIB019780
Drug Name	DR-4004
Synonyms	compound 7 [PMID 10052959]
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[525428]
Structure		Download 2D MOL
Formula	C26H30N2O
InChI	InChI=1S/C26H30N2O/c29-25-26(16-7-11-22-10-6-12-23(27-25)24(22)26)15-4-5-17-28-18-13-21(14-19-28)20-8-2-1-3-9-20/h1-3,6,8-10,12-13H,4-5,7,11,14-19H2,(H,27,29)
InChIKey	JBQOYPLKTTXLSQ-UHFFFAOYSA-N
PubChem Compound ID	9843179
PubChem Substance ID	14804979, 24140972, 44941252, 74425087, 103266893, 104010589, 231911574, 252166641
Target and Pathway
Target(s)	5-hydroxytryptamine 7 receptor	Target Info	Antagonist	[526655]
KEGG Pathway	Ras signaling pathway
	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome	Serotonin receptors
Reactome	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 525428	Tetrahydrobenzindoles: selective antagonists of the 5-HT7 receptor. J Med Chem. 1999 Feb 25;42(4):533-5.
Ref 526655	J Med Chem. 2003 Jul 3;46(14):2795-812.Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).

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Drug Information