Drug General Information
Drug ID	D01SGK
Former ID	DIB006208
Drug Name	Opicapone
Synonyms	BIA-9-1067
Indication	Parkinson's disease [ICD9: 332; ICD10:G20]		Phase 3	[532159]
Company	Portela & Ca SA
Structure		Download 2D MOL 3D MOL
CAS Number	CAS 923287-50-7
Target and Pathway
Target(s)	Catechol-O-methyl-transferase	Target Info	Inhibitor	[532159]
BioCyc Pathway	L-dopa degradation
	Dopamine degradation
	Noradrenaline and adrenaline degradation
KEGG Pathway	Steroid hormone biosynthesis
	Tyrosine metabolism
	Metabolic pathways
	Dopaminergic synapse
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	Dopamine receptor mediated signaling pathway
PathWhiz Pathway	Tyrosine Metabolism
WikiPathways	Methylation Pathways
	Metapathway biotransformation
	Estrogen metabolism
	Biogenic Amine Synthesis
	Dopamine metabolism
	Phase II conjugation
	Neurotransmitter Clearance In The Synaptic Cleft
References
Ref 532159	Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor. Clin Pharmacokinet. 2013 Feb;52(2):139-51.
Ref 532159	Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor. Clin Pharmacokinet. 2013 Feb;52(2):139-51.

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